When a sickly young girl suddenly becomes obsessed with inventing new things, her family and friends are all puzzled. "What has gotten into Myne?" they wondered, never dreaming that the answer is not a "What" but a "Who": Urano Motosu, a book-loving apprentice librarian who died in an earthquake in Tokyo who somehow found herself in Myne's body! And since Myne's world is still in a medieval stage, where books can only be owned by the elite, the new Myne intends to do everything she can to bring her beloved books to the masses in the time she has left.

Misaki Ayuzawa is the first female student council president at a once all-boys school turned co-ed. She rules the school with strict discipline demeanor. But she has a secret, she works at a maid cafe due to her families circumstances. One day the popular A-student and notorious heart breaker Takumi Usui finds out her secret and makes a deal with her to keep it hush from the school in exchange for spending some time with him.