Giulio is a widower, struggling to raise three sons, Marco, Rudi, and Mimmo, as best he can. He lives in Rome's working-class Garbatella neighborhood and runs a wine shop with his two brothers. Lucia, meanwhile, comes from Milan's middle-class background; she's divorced and trying to rebuild her life with her two daughters, Eva and Alice. The two meet by chance and recognize each other: they had a fling as teenagers, many years earlier. Yet first love is never forgotten, and so Giulio and Lucia find themselves together again. Their meeting, however, changes not only the lives of a man and a woman, but also those of two families as different as could be. Two families who find themselves living under the same roof without even having had the time to get to know each other well.

Ciao Darwin is a variety game show format from Italy sold under licence to several countries, including Romania, Hungary, Poland, Serbia, Canada, USA, China and Greece. There are two competing teams of about 50 people each, usually made up of people who fit certain opposing stereotypes. In each game two members of the audience are selected at random, one from each team, indicated by a light in front of them which remains illuminated when all the other team members' lights have gone off. The games involve contestants competing in acts of bravery, style and talent, some of which are designed to humiliate the contestants, especially an assault course which was introduced with the Italian version in 2010, and the Finale which is a water tank game.

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