A widowed trucker fends off isolation in the company of a dog named Girl, two bickering sisters try to reconcile their differences and a down-and-out circus clown and his stripper girlfriend must fight the temptation of crime on the road. Their common companion is an angry disc jockey at odds with a desperate boss. All these people will find their lives intertwined by the hand of fate. And before the night gives way to day, some will breathe their last breath... Outside Ozona.

A devious worker manages to trick a dim-witted security guard into letting her sneak out a small quantity of an unknown substance. The woman takes the vial to a remote warehouse, but she is brutally murdered by an unseen menace before she is able to receive payment for her pilfering! Next up we meet the likely body count material and massacre applicants at a Los Angeles ‘talent’ show.