An edge-of-your-seat view into the lives of everyday heroes committed to one of America's noblest professions. For the firefighters, rescue squad and paramedics of Chicago Firehouse 51, no occupation is more stressful or dangerous, yet so rewarding and exhilarating. These courageous men and women are among the elite who forge headfirst into danger when everyone else is running the other way and whose actions make the difference between life and death.

The New York office of the FBI brings to bear all their talents, intellect and technical expertise on major cases in order to keep their city and the country safe.

A showdown decades in the making brings the Donovan family legacy full circle. As the events that made Ray who he is today finally come to light, the Donovans find themselves drawn back to Boston to face the past. Each of them struggles to overcome their violent upbringing, but destiny dies hard, and only their fierce love for each other keeps them in the fight.

A young man diagnosed with lymphoma decides to eschew medical treatment and embark on an odyssey of debauchery, self-destruction, and self-discovery through New York City.

A precocious high school senior finds an unlikely lifeline in her court-mandated therapist after she is ostracized from school after a sexual transgression with her English teacher goes viral.