Frank Martin puts the driving gloves on to deliver Valentina, the kidnapped daughter of a Ukrainian government official, from Marseilles to Odessa on the Black Sea. En route, he has to contend with thugs who want to intercept Valentina's safe delivery and not let his personal feelings get in the way of his dangerous objective.

After witnessing her parents’ murder as a child in Bogota, Cataleya Restrepo grows up to be a stone-cold assassin. She works for her uncle as a hitman by day, but her personal time is spent engaging in vigilante murders that she hopes will lead her to her ultimate target: the mobster responsible for her parents' death.

Pran Boon, or Hunter Boon, saves a child's life by killing a young Sming that attacked him. Little did he know that the young Sming was not the only one in the area. After having witnessed Pran Boon killing her son, mother Sming sets out to Pran Boon's village, seeking revenge that leaves Pran Boon's wife dead and his daughter injured. Knowing he and his daughter would never be safe again until the Sming is dead, Pran Boon begins his hunt for the most dangerous hunter in the jungle with the support of Pran Hlong, an immigrated Chinese hunter who seems unlikely to be an ordinary hunter.