Minnie Goetze is a 15-year-old aspiring comic-book artist, coming of age in the haze of the 1970s in San Francisco. Insatiably curious about the world around her, Minnie is a pretty typical teenage girl. Oh, except that she’s sleeping with her mother’s boyfriend.

Dave and Joe, just evicted from their Oakland apartment, turn to stealing cars and dealing Fluoride to make their financial ends meet. One night they find Summer Hayes, star of a popular 1990's teen soap, in the trunk of a stolen automobile. Shoot-outs, car chases, and overdoses ensue. In the Fluoride heightened world of "Medias Res", nothing is what it at first appears to be.