From absolute poverty to absolute power! "El Don" is the saga of a common man with uncommonly fierce ambition who rises to rule an empire of unspeakable evil only to discover that the love he thought he had forgotten still rules what is left of his heart.

Five Stories separate about our inability to face our own fears and shortcomings as human beings.

A beautiful seductress draws a man in the midst of a mid-life crisis into a sordid world of drugs, crime, and debauchery. Alejandro is down on his luck. Unemployed and loveless, he falls hard for beautiful Vanessa when fate brings the two together seemingly by chance. But Vanessa's boyfriend is a hit man for the mob, and despite at first feeling swept up in circumstances beyond his control, Alejandro soon realizes that in order to regain his confidence, he must embrace his destiny.

After the death of his father, young Pedro Pérez Delgado (Maisanta) becomes the man of the house. To help support his mother and sister, he begins working for Colonel Macías, who betrays his trust by courting his sister Petra despite being married, dishonoring the family name—a family honor his father had asked him to defend at any cost. Amid stories of love, betrayal, and vengeance, the figure of Maisanta is forged. The fair-skinned, blond-haired boy whom many called “The American” would eventually become a legend, known by his battle cry: Maisanta!

Investigating the murder of a drag, the journalist Heriberto Camargo discovers that the crime is part of a plot of police killings attributed to a character known as Vincent. The chronicles published by Camargo and his investigations to uncover the motive for the crimes confront Commissioner Sangretti.

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Under the command of the Liberator Simón Bolívar, on June 24, 1821, the patriotic army fought to the death against the forces loyal to the Spanish crown with the goal of achieving, at all costs, the independence of Venezuela.