Arrogant, self-centered movie director Guido Contini finds himself struggling to find meaning, purpose, and a script for his latest film endeavor. With only a week left before shooting begins, he desperately searches for answers and inspiration from his wife, his mistress, his muse, and his mother.

Paralyzed from a crash, Nicola falls for his physiotherapist Lucia. Franco and Manuela seek fertility treatment in Barcelona. Filippo and Fosco, a gay couple, plan their wedding. Ernesto, a waiter, has an affair with Spanish cook Cecilia.

Four intertwined stories on the joys and sorrows of love.

Giada is a overachieving student who works to pay for college. Riccardo is a spoiled brat who answers her tutoring ad in order to improve his abysmal grades. She's shy and homely. He's handsome and brazen. As they say, opposites attract.

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