Families, friends, enemies and lovers experience life-changing events in the large upstate New York city of Port Charles, which has a busy hospital, upscale hotel, cozy diner and dangerous waterfront frequented by the criminal underworld.

Sarah and Josh are married suburbanites. After a car accident, Sarah suffers blackouts and ends up pregnant though Josh is sterile. As her life spirals she hides a camera in her home and unlocks a horrific secret with far-reaching consequences.