Blanca Ferrando is a young woman who became blind at the age of twelve, due to a dramatic fire in which her older sister Beatrice died and which was caused by her violent boyfriend, Sebastian. This tragedy made her develop a very strong sense of justice to the point of pushing her to join the police. Blanca is helped by her most trusted friends: her guide dog Linneo, a female bulldog who protects and comforts her in the most difficult moments, and her beautician friend, Stella. After overcoming her work challenges, she finds herself facing sentimental ones: torn between two men, Inspector Michele Liguori, a man of many secrets, and Nanni, a young cook.

The Catholic Church secretly investigates Caravaggio as the Pope weighs whether to grant him clemency for killing a rival.

In Italy, a woman fears her sister has been kidnapped; Inspector Enzo Avolfi fears it's worse. They team up to rescue her from a sadistic killer known only as Yellow.

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Andrea is a shocked boxer who arrives late for a worthless fight, but he's finally determined to change everything.