After many years spent at the “Cheers” bar, Frasier moves back home to Seattle to work as a radio psychiatrist after his policeman father gets shot in the hip on duty.

Five brothers and sisters are determined to stay together following the tragic loss of their parents.

Nikki White pursues her dream of being a Las Vegas showgirl, while her husband, Dwight, tries to break into professional wrestling.

After moving to Boston from Virginia, to spy on his sister who just started college, Boyd finds himself working for the student union where he raises hell more often than he should.

Typical teenager Sam Collins and his friends secretly fight virus monsters by transporting themselves into the computer.

Pat Riley, an obnoxious busybody of indeterminable sex, meets and falls in love with Chris, a sensitive, caring person also of indeterminable sex. Their relationship suffers because Pat's a lout, and cannot decide on a direction for their life. Meanwhile, Pat's neighbor Kyle falls further and further into obsession with Pat, fascinated by their indeterminate sexuality.

In this Christmas special, Malcolm and the evil Kilokahn have finally tracked down Servo. Kilokahn has ordered Malcolm to strand up Christmas lights to pin point him. When Kilokahn finds out that Sam Collins is Servo he tries to destroy him. Kilokahn turns on Malcolm and tries to destroy him as well. Now Sam and Malcolm have to work together after secretly being enemies all along. Servo now has to defeat Kilokahn in a finale battle.