Leila and Damien are deeply in love. Despite his bipolar disorder, he tries to pursue his life with her, knowing he may never be able to offer her what she desires.

1542, the year of Jacques Cartier's second mission to Canada. Pregnant by a man other than her future husband, the expedition's commander, the young Marguerite de la Rocque is abandoned on a deserted island off the coast of Newfoundland with the man who raped her and his maid. She will remain there for two years, surviving hunger, cold, despair, and madness.

Jacques, a morgue employee haunted by nightmares, develops a invisible serum made from transparent little fish.