Giulio is a widower, struggling to raise three sons, Marco, Rudi, and Mimmo, as best he can. He lives in Rome's working-class Garbatella neighborhood and runs a wine shop with his two brothers. Lucia, meanwhile, comes from Milan's middle-class background; she's divorced and trying to rebuild her life with her two daughters, Eva and Alice. The two meet by chance and recognize each other: they had a fling as teenagers, many years earlier. Yet first love is never forgotten, and so Giulio and Lucia find themselves together again. Their meeting, however, changes not only the lives of a man and a woman, but also those of two families as different as could be. Two families who find themselves living under the same roof without even having had the time to get to know each other well.

Sixteen year old Rocco's two aims in life are to get laid and to see his favorite pop star in concert with his two best friends. When a bullying incident at school forces Rocco to come out to his divorced middle-class parents their liberal leanings are severely tested. Luckily his two friends stand by him and join him in running away from home (in his parents stolen car) to see their favorite singer in concert, followed hot on their heels by his neurotic mother and eccentric gran.

Paolo is an outgoing and handsome real estate broker married to Simona, a beautiful woman from the rough outskirts of Rome who has become an author of spicy bestsellers and is pregnant with their child. Betta, Paolo’s sister and her husband Sandro organise a dinner party with Paolo, Simona and their childhood friend, the eccentric musician Claudio. During the lively gathering Paolo reveals what he would like to name his son, causing reactions to steam up and a torrent of revelations to follow reaching climactic proportions.