The story of haves and have-nots in a world in which there's almost nothing left to have. 200 years after the apocalypse, the gentle denizens of luxury fallout shelters are forced to return to the irradiated hellscape their ancestors left behind — and are shocked to discover an incredibly complex, gleefully weird, and highly violent universe waiting for them.

Doogie Howser is a doctor. He is also a 16-year-old genius who graduated college at age 10 and finished medical school at age 14. But he is still a teenager, with normal teenage friends and problems. But unlike a normal teenager, he is just learning to drive while also consulting on serious medical cases like heart transplants.

Jimmie Rainwood was minding his own business when two corrupt police officers (getting an address wrong) burst into his house, expecting to find a major drug dealer. Rainwood is shot, and the officers frame him as a drug dealer. Rainwood is convicted of drug dealing, based on the perjured evidence of a police informant. Thrown into a seedy jail, fighting to prove his innocence is diffucult when he has to deal with the realities of prison life, where everyone claims they were framed.

When old martial arts master Master Tak disappears, his best student, Jet, steps in to find him. However, when he learns that Tak's life is in danger, he decides to protect him at all costs.

Wayne Dobie is a shy cop whose low-key demeanor has earned him the affectionate nickname "Mad Dog." After Mad Dog saves the life of Frank Milo, a crime boss and aspiring stand-up comedian, he's offered the company of an attractive young waitress named Glory for a week. At first both are uneasy about the arrangement, but they eventually fall in love. However, the situation becomes complicated when Milo demands Glory back.

In ancient China, an aimless young man falls in love with the Emperor's beautiful daughter, and goes on a journey with his supposedly long-lost uncle in search of riches.