S. Muthu (aka Smoothu) , who is a pickpocket expert, meets with an accident and after that incident, he starts to suffer from a disease, alien hand syndrome, which means that his left hand wouldn't be under his control. Now, what problems this syndrome creates and how does it bring about a change in Smuthu's life?

Human rights commission of India appoint Sivagami, an ex-IAS officer, to interrogate the police officials in-charge of the encounter of five youngsters, for allegedly raping and murdering an innocent girl, Vindhya and find out what had actually happened. Sivagami's interrogation leads to a series of revelations that shock Sivagami and the parents of the youngsters who died in the encounter.