A top-secret experiment spawns two highly intelligent life-forms: Einstein, a golden retriever with an IQ of 175; and The Outsider, a deformed monstrosity that exists to kill... and avenge its creators. When the Outsider escapes into the jungles of South America, the government sends in some ex-military convicts to catch the beast. But what starts out as a high-speed chase ends up in bloody carnage. Only Einstein knows the Outsider's motives, and only the canine can outsmart the creature. Now, it's a battle of beasts as man's best friend confronts man's worst nightmare.

The simple task of babysitting a lounge singer's wife turns into a nightmare for Ginger, Sean and Ricky, three unsuspecting film characters that become self-aware of their own existence in a fictional movie. With an eager determination to defy the writer's outrageous ideas, the characters must quickly think of ways to break out of their predestined roles and into a real and unpredictable narrative of their own making. But when the film's director and producer decide to abandon their current cast and complete the project with an alternative approach to the material, Sean, Ricky and Ginger have some plot twists of their own for the powers that be in this surreal, outlandish comedy.