Duncan MacLeod cannot die -- he is a 400-year-old immortal, who has seen his share of humanity's history. Still, he risks his life in battle against other immortals and tries to save people from harm.

In 1830s France, pianist/composer Frédéric Chopin is pursued romantically by the determined, individualistic woman who uses the name George Sand.

Descartes left the Jesuit college where he had spent his childhood. He doubted the knowledge that had been instilled in him, with the exception of mathematics and geometry. He enlisted in the army of the Prince of Nassau in Breda. Upon his return, he wanted to escape the worldly atmosphere and devote himself to his studies. During an intense night, he found the foundations of a new science.

An eccentric bounty hunter named Providence captures and sets free a criminal in order to collect the same bounty over and over again in different states, until they discover that a local sheriff is up to something crooked.