The trials and triumphs of one of the wealthiest and unhappiest families of the United States, the Gettys. Originally planned to be told over multiple seasons and spanning the twentieth century, the series begins in 1973 with the kidnapping of John Paul Getty III, an heir to the Getty oil fortune, by the Italian mafia in Rome.

Mario Bambea, an italian Intellectual, after a car accident begins to suffer of double personality. In the day, Mario is an intellectual while in the night, becomes a rude comedian.

While the Calabrian mafia is spreading its influence in the early 70s, Antonio, son of the high-ranking 'Ndrangheta boss Giacomo Zagari, finds himself killing more and more frequently, ultimately realising that he isn't suited to this extreme lifestyle. While his generation rises up in factories, universities and public squares, Antonio finds the strength to defy his father, rejecting his legacy.

Marta, a single mother promised to an older farmer in the aftermath of WWII, forges an unlikely friendship with Lorenzo, the village's openly gay "wedding planner." In the conservative backdrop of rural Southern Italy, Lorenzo introduces her to a hidden community of gays, sparking Marta's journey to challenge societal prejudices. In the first year of women's suffrage in Italy, Marta navigates her evolving role as a woman, breaking barriers and finding her place in a changing world.

Luca, a diction teacher, saves the life of a student which is the offspring of the famous "Serranò" criminal family. Out of nowhere, members of the Serranò family burst into Luca's life to repay him without accepting a "no" as an answer.

Marcello is a Calabrian boy who dreams of becoming a footballer and lives with his mother, Tereza, of Arbëreshë origin, in the popular neighborhood called "Aranceto". During the imminent period of the 1990s World Cup, he meets Andrea Viscomi, a late career footballer, captain of the local football team, U.S.Collidoro. Their lives are intertwined. The friendship with the footballer rekindles in the boy the desire for a father figure that he has never had and in the footballer a forgotten carefree time, which has been lost above all due to his involvement in match-fixing. The coming-of-age novel of Marcello crosses the descending parable of Andrea's career, in the sign of a friendship necessary for both.

Felice is a twenty-year-old boy from a working-class neighborhood. He buys a grand piano with money from a loan shark and with the help of Noemi, a young girl of the same age he met in the library, he plays in the squares of Campania for passers-by and tourists. The security guard Enzo, after an argument, destroys his piano into many pieces. Chased by loan sharks, he finds himself in the back of a church. He is given a jacket and tie and is sent to the altar in front of the dead man's relatives. He begins to make a speech in commemoration of a deceased person he doesn't even know, but the words flow spontaneously, cleanly, moving and exciting. After that speech he will become the funeral boy, the orator.

Lisa is a young 25 year old who has dreamed of cinema since she was a child. For her, the role of the runner is an important milestone: it is her arrival in the world of cinema, but also the starting point for a brilliant career. She is finally on a set, starting a relationship with Sonja, protagonist and film star. What more could you want from life? What could go wrong? But the actress has a dark past that comes back to look for her at the most unexpected moment. Accused of Sonja's murder, the girl is forced to flee. Lisa runs, runs to save her life and to find the evidence that will exonerate her and allow the real murderer to be convicted.