Don Matteo is a thoroughly ordinary Catholic priest with an extraordinary ability to read people and solve crimes. He’s a parish priest who never met an unjustly accused person he didn’t want to help.

Arturo Meraviglia is a struggling impresario who has to take care of Gioele and Rebecca, two children "inherited" by an old uncle. When he realizes that little Gioele has superpowers, his luck changes.

Getting ready for the wedding that will unite two very different families- the humble Italian taxi driver Cristoforo Colombo and his wife Rosy, and the rich Italian-Americans Alessandro and Patricia Di Giacomo.

Five survivors desperately seek a safe haven to escape a world pandemic. But they soon realize they must face their deepest fears.