An elite team of FBI profilers analyze the country's most twisted criminal minds, anticipating their next moves before they strike again. The Behavioral Analysis Unit's most experienced agent is David Rossi, a founding member of the BAU who returns to help the team solve new cases.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Allison Dubois works in the District Attorney’s office using her natural intuition about people and her ability to communicate with the dead to help to solve crimes. Her dreams often give her clues to the whereabouts of missing people.

To improve its relations with Muslim countries, the United States government sends comedian Albert Brooks to south Asia to write a report on what makes followers of Islam laugh.

Emma is an aspiring sound designer in LA stuck paying the bills by creating sound effects for pornos. Barkley has secretly dropped out of her Masters program but still pretends to go every morning so her Polish immigrant family doesn’t have to find out she fizzled. And Rachel is the best elementary school teacher in the world but has a completely empty life when she’s not at school. After hearing that Emma’s parents have abandoned her failed boat building project to the trash collectors, the three millennials drive to rural Maryland to rescue and restore both the boat and their pride. As they build, they learn from each other and two colorful locals what may be required to reconcile their dreams with their realities.

Jo's world is thrown into utter disarray when her wife Amanda passes away and she starts chasing a dream that she and Amanda had once shared - starting a family together. Jo asks her late wife's brother, Jamie, to be her sperm donor and craziness ensues.

Rekha is broke, jobless, and often drunk. When she overhears surprising news about her absentee father, she embarks on a road trip with her best friend to find him.