The unlikely police pair Verena Berthold and Otto Garber are part of a special task force investigating organized crime in Berlin. He comes from the east, she from the west of Berlin. He's a redneck, she's from a better background. This causes conflict. Over time, things start to sizzle between the two. Their team includes the agile German-Turkish Yücsel and the sluggish Georg, who, like Verena and Otto, are constantly bickering. The department manager is Lothar Reddemann. Sputnik is a former colleague of Otto's from the People's Police and is constantly coming up with new business ideas for stores and pubs where the team meets.

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An international group of film students finds a disturbing video clip on the dark web which seems to contain poltergeist phenomena. Agreed that it's just what they need for their latest documentary project the group travels to the sanatorium shown in the video clip. Once there, they rig up their camera equipment and start to explore the possible ghost activities - until the true horror begins.

1945: The red army stands at the gates of Berlin. In their desperation the Nazis turn to the most obscure Scientists. Through cruel experiments a new secret Weapon has been created - unstoppable and alive. A Russian attack destroys the lab, but the weapon - buried underneath the ruins - is immortal. Lost in time, it lurks in the darkness, only to return again. 2012: Punk-Rock legend Spike Jones leads a group of friends into the ruins of the old Nazi Lab. The complex shall be cleaned up for the reunion concert of his band. Believing they would help a poor soul, they free the beast from its prison. But the creature of the Nazis does not know about thankfulness. Again the smell of blood fills the old laboratories and screams of terror echo through the darkness. As now, the Werewolf starts his war against humanity.

Mag wants to boost her modelling career by undergoing plastic surgery. Joined by her sister Nicole and her friend Hanna, they visit the surgery clinc. However, the surgeons have other things in mind than just a simple job...