Libido starts with the simple, unpretentious life of the couple Corazon and Abner who manage the family farm. The complication in their lives began with the arrival of Corazon's sister Jacinta and husband Bobby. The minute Jacinta sets eyes on Abner, and Corazon on Bobby, two promiscuous affairs happened. This tale of partner swapping, homosexual encounters and other occurrences may prove mind boggling to many. How will these affairs affect the lives of two couples?

Set at the inauguration of the new President is the inter-woven tales of people dealing with daily lives: their relationships, desires and their means of survival. A taxi driver trying to stop his best friend from leaving for the province while his ex-wife comes back to his life; a young actor doing extra job as male prostitute; a Fil-Am trying to fill his need for drugs; and a young cigarette vendor who also act as pimp at night. All of them get through their harsh realities with hopes of a better tomorrow while their fate awaits them to cross its path in the uncaring streets of Manila.