The show follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.

While attending a Hollywood premiere with a famous action star, a crazed fan pulls a gun—but her movie hunk turns into a coward, and it's Vallery who becomes the hero. Suddenly, she's thrown into a world of action and danger as owner of a Hollywood protection agency, Vallery Irons Protection (V.I.P.), taking risks to protect others at a price few are willing to pay.

In ancient Egypt, peasant Mathayus is hired to exact revenge on the powerful Memnon and the sorceress Cassandra, who are ready to overtake Balthazar's village. Amid betrayals, thieves, abductions and more, Mathayus strives to bring justice to his complicated world.

Ray Owens is sheriff of the quiet US border town of Sommerton Junction after leaving the LAPD following a bungled operation. Following his escape from the FBI, a notorious drug baron, his gang, and a hostage are heading toward Sommerton Junction where the police are preparing to make a last stand to intercept them before they cross the border. Owens is reluctant to become involved but ultimately joins in with the law enforcement efforts.

An elite multi-agency taskforce tracks down Los Angeles's 100 most wanted fugitives as they struggle to balance their work and personal lives.