Sydney Bristow, an agent who has been tricked to believe she is working for the U.S. government, is actually working for a criminal organization named the Alliance of Twelve. Upon learning this, Sydney becomes a double agent for the real CIA.

This low budget action film, originally titled "The Return of Dolemite", follows Rudy Ray Moore as Dolemite, who returns from Africa with superpowers gained from drinking Voodoo Juice.