Following the adventures of a bunch of nobodies who get up to a whole lot of nothing in the fictional prairie town of Dog River, Saskatchewan, Corner Gas focuses on the life (or lack thereof) of Brent LeRoy, proprietor of a gas station that is the only stop for miles around and a hub of action on the Prairies.

Forensics students arriving on an isolated island "body farm" get to try out their CSI skills on a bunch of corpses under the watchful eye of their grumpy professor. The island used to house a state penitentiary, where the authorities were experimenting on death row inmates, and now the bodies won't stay still.