Rookie FBI agent Jo Dee Foster has been assigned to work on the case of the Psycho Killer, a psycho killer who has psycho-killed over 120 people. But to learn more about his target, he's forced to meet Dr. Animal Cannibal Pizza, a famous doctor turned cannibal who ate pizzas with human body parts. Meanwhile, Jo's girlfriend, Jane Wine, has just stolen $400,000 in cash from her money-hungry boss, Mr. Laurel, so she and Jo can be happy, but gets lost in a horrible storm and stops at the Cemetery Motel, where the owner, Antonio Motel, is dominated by his insane mother.

When a group of young Spanish tourists travel to Venice for a bachelorette party, they are met by angry locals who are not keen on foreigners and soon they find themselves fighting for their lives.

The Film centers around an American-style fast food restaurant in Milan, the employees who work there and the clients that frequent the place.

Two estranged brothers are brought back together when a script they're writing comes to life and sends a poorly rendered digital shark to hunt them down in this meta take on the sharksploitation genre.