Joe and Benny are two cowboys on tour in the Wild West as a singing duo, usually without a penny in their pockets to spare. Joe is a talented rodeo-rider, which fascinates the little girl Susanne and gives her the wish to have him as a father. Her mother Maria, however, is to marry the evil, rich farmer Dave. Susanne wants to stop the wedding, so she sneaks aboard Joe and Benny's wagon to persuade them to intervene. Dave brands them as kidnappers, forcing them to flee as outlaws to one of the families tyrannized by Dave. Together, they strike back at Dave, at which point Maria sees that he's the wrong man for her.

The son of a working-class man, Harry Brenner studied medicine at the ABF and quickly made a career as a doctor in Berlin. His lifestyle and his demanding wife swallow up a lot of money, so he takes on any part-time work. After a gross dereliction of duty, he is transferred to Bothenow. He meets Eva again, whom he knows from his student days and who now works here as a nurse. The two hit it off and Dr. Brenner slowly begins to change his life. In doing so, he increasingly comes into conflict with his wife. Their different views on life eventually lead to a separation.