In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

John Reese, former CIA paramilitary operative, is presumed dead and teams up with reclusive billionaire Finch to prevent violent crimes in New York City by initiating their own type of justice. With the special training that Reese has had in Covert Operations and Finch's genius software inventing mind, the two are a perfect match for the job that they have to complete. With the help of surveillance equipment, they work "outside the law" and get the right criminal behind bars. 

Alicia Florrick boldly assumes full responsibility for her family and re-enters the workforce after her husband's very public sex and political corruption scandal lands him in jail.

Shrewd, savvy U.S. Attorney Chuck Rhoades and the brilliant, ambitious hedge fund king Bobby "Axe" Axelrod are on an explosive collision course, with each using all of his considerable smarts, power and influence to outmaneuver the other. The stakes are in the billions in this timely, provocative series.

Former Syracuse, New York, police detective Carrie Wells has hyperthymesia, a rare medical condition that gives her the ability to visually remember everything. She reluctantly joins the New York City Police Department's Queens homicide unit after her former boyfriend and partner asks for help with solving a case. The move allows her to try to find out the one thing she has been unable to remember, which is what happened the day her sister was murdered.

A police officer patrols a Philadelphia neighborhood hard-hit by the opioid crisis. When a series of murders begins in the neighborhood, Mickey realizes that her personal history might be related to the case.

After working as a drug courier and getting into a brutal shootout with police, a former boxer finds himself at the mercy of his enemies as they force him to instigate violent acts that turn the prison he resides in into a battleground.

Follow the first human mission to Mars, exploring the challenges of taking the first steps toward interplanetary colonization. The story focuses not only on the astronauts, but also on their families and loved ones, as well as the ground team on Earth.

Lucy and Lucien are two childhood friends who share a deeply troubled past and struggle to maintain their sanity and sobriety as they cut their teeth in the New York City arts & theater scene. As their breakout moment arrives, both are forced to grapple with a legacy of childhood trauma, addiction, and loss. They must rely on their chosen family of artists and sex workers to help bring them through their dark night of the soul.

A young woman with Asperger's tries to find her first boyfriend with a little help from her older sister.