After her successful career in Chicago, Elsbeth Tascioni, an astute but unconventional attorney, utilizes her singular point of view to make unique observations and corner brilliant criminals alongside the NYPD.

Skeptical forensic psychologist Kristen Bouchard joins priest-in-training David Acosta and technology expert Ben Shakir as they investigate supposed miracles, demonic possessions, and other extraordinary occurrences to assess for a scientific explanation or if something truly supernatural is at work.

When struggling voice actress, Gloria, discovers her agent failed to tell her that her claim-to-fame cartoon is being remade, she sets her sights on reprising her role as the famous BioBoy.