Don Matteo is a thoroughly ordinary Catholic priest with an extraordinary ability to read people and solve crimes. He’s a parish priest who never met an unjustly accused person he didn’t want to help.

Love, business, anxieties, friendships, feuds, and resentments paint the picture of the main story, that of a group of criminals who for nearly fifteen years, from 1977 to 1992, cherished an illusion: that of conquering Rome. The Lebanese, Freddo, Dandi, Patrizia, and Commissioner Scialoja are some of the characters inspired by the true story of the Magliana gang. As stated by Aldo Grasso, the first season of the series gives more space to the crime scene, that is, the criminal exploits of the Magliana gang, while the second season delves deeper into the "behind the scenes" of the crime: thus, the gang's repositioning after a key plot event, and the effects and questions this has provoked in the protagonists' consciences.

The entire Rienzi family eagerly awaits their summer return to the country house, where each member hopes to experience a truly special stay. Vittorio, the father—recently struck by a heart attack—and his wife Marinella dream of revitalizing their troubled marriage; their daughter Eleonora, a single mother, hopes to rekindle a romance with the local heartthrob, Antonio; and their fifteen-year-old son Matteo—who has failed three school subjects—aims to win over the beautiful young Fiorenza, whom he has thought about all winter long. As their dreams and hopes collide with reality, the Rienzi family will experience a summer that proves pivotal and transformative for their lives.

Ambulance-chasing lawyers takes on the case of a convicted murderer who, just being released after doing 27 years in jail, claims he was innocent.

Recovering from a severe nervous breakdown and a great fan of thriller films, twenty-two-year-old Niccolò decides to go to the cinema with his dearest friend Viola. They are joined by their friends Ambra, Valerio, Matteo and Clelia, with whom they go to the largest multiplex in their city, a place at the center of several sinister urban legends. When, at the end of the film, the group decides to spend the night inside the cinema to make fun of the maniacal and ambiguous guard, the six will find themselves grappling with a macabre secret.