Heroic Officer 444 battles The Frog and his criminal gang for possession of Haverlyte, a powerful formula that, if it fell into the wrong hands, would give its owner enough power to control the world. And, taking no chances, The Frog sends his chief henchwoman, a seductive vamp named The Vulture, to tempt Officer 444 to stray from his sworn duty to save the world from The Frog's nefarious plans.

A newspaper publisher finds out that his wild daughter has fallen in with a ring of gamblers. A reporter who has infiltrated the gang to get a story falls in love with the gang's female leader, and when the two are caught in a police raid, they find themselves in equal amounts of trouble.