The daily lives of the inhabitants of "le Mistral", an imaginary neighbourhood in the Mediterranean port city of Marseille, where wealthy families cross paths with the less than rich.

Clem follows the life of a young teenager, Clémentine, who becomes a mother at the age of sixteen, at the centre of tensions between her parents and Julien, the father of her child Valentin. It deals with the problems of teenage life and that of a mother with a strong personality.

In Paris of the near future, a dating app matches singles with their soul mates by mining their brain data. But decoding true love comes at a price.