Given superstrength and durability by a sabotaged experiment, a wrongly accused man escapes prison to become a superhero for hire.

Detectives Marcus Burnett and Mike Lowrey of the Miami Narcotics Task Force are tasked with stopping the flow of the drug Ecstasy into Miami. They track the drugs to the whacked-out Cuban drug lord Johnny Tapia, who is also involved in a bloody war with Russian and Haitian mobsters. If that isn't bad enough, there's tension between the two detectives when Marcus discovers that playboy Mike is secretly romancing Marcus’ sister, Syd.

When six raiders kill her husband, child and workers on her ranch, a white woman raised by the Commanche' claims an Indian blood rite.