Columbo is a friendly, verbose, disheveled-looking police detective who is consistently underestimated by his suspects. Despite his unprepossessing appearance and apparent absentmindedness, he shrewdly solves all of his cases and secures all evidence needed for indictment. His formidable eye for detail and meticulously dedicated approach often become clear to the killer only late in the storyline.

Los Angeles County medical examiner Quincy routinely engages in police investigations.

A saga centered on the Tierneys, a multi-generational family of New York City Police officers. The family's moral codes are tested when Ray Tierney investigates a case that reveals an incendiary police corruption scandal involving his own brother-in-law. For Ray, the truth is revelatory, a Pandora's Box that threatens to upend not only the Tierney legacy but the entire NYPD.

New York gangster Ben 'Bugsy' Siegel takes a brief business trip to Los Angeles. A sharp-dressing womanizer with a foul temper, Siegel doesn't hesitate to kill or maim anyone crossing him. In L.A. the life, the movies, and most of all strong-willed Virginia Hill detain him while his family wait back home. Then a trip to a run-down gambling joint at a spot in the desert known as Las Vegas gives him his big idea.

In this strange western version of Moby Dick, Wild Bill Hickok hunts a white buffalo he has seen in a dream. Hickok moves through a variety of uniquely authentic western locations - dim, filthy, makeshift taverns; freezing, slaughterhouse-like frontier towns and beautifully desolate high country - before improbably teaming up with a young Crazy Horse to pursue the creature.

A tough police detective escapes from custody after being framed and arrested for the murder of his ex-wife, and must now find the real killer and prove his innocence.

Jackie Pruit is the girlfriend of notorious gangster Joe Bomposa. When it looks as if Bomposa's goons are threatening Jackie's life, the FBI moves in to protect her, hoping that she'll have incriminating evidence. Veteran agent Charlie Congers is assigned to watch over Jackie, and while it soon becomes apparent that she knows almost nothing about Bomposa that would be of any use to the FBI, he falls in love with her. Bomposa decides it would be more convenient to have Jackie out of the way, ordering her to be executed. Bomposa's henchmen slip through FBI security and murder her, but now they have to answer the angry and vengeful Congers.

A dabbler-in-crime and his assistant hire an ex-police reporter to recover some stolen papers.