Brainy scientist Sarah, a doctoral student at Columbia University, is weeks away from following her very married boyfriend to Ohio when her mother dies suddenly, leaving Sarah the owner of a small but beloved Christian bookstore in the Bronx. Tasked with planning a culturally respectful funeral befitting the family matriarch, Sarah must juggle the expectations of her loving yet demanding family while navigating the reappearance of her estranged father all while grappling with what to do with the bookstore. Aided by an only-in-New York ensemble of Eastern European neighbors, feisty African aunties and a no-nonsense ex-con co-worker, Sarah faces her new responsibilities while figuring out how to remain true to herself.

Alienated from his conservative Jewish family and community, a promising, young, gay schoolteacher seeks solace in New York's barebacking scene.