OB tells the story of funny incidents at the OKTV television station office. All these incidents often occur due to the naivety of Sayuti, the Office Boy in the office. Placed in the kitchen, the innocent Sayuti has to interact with fellow workers, such as Odah, who acts like a ruler, Ismail, who often acts cool, and Susi, a janitor who falls in love with Sayuti.

Siena is able to see signs that people will die. The sign appeared on Brama, someone she loves. Siena tries hard to prevent Brama's death.

For the sake of her mother’s treatment, Gendis works at a night club as DJ. Moreover, the mother has to be rushed to hospital due to critical condition. The hospital’s deposit fee is exorbitant. Gendis’ friend, Deborah, Brenda, and Galuh, suggest that she sells herself to Mr Pulung. Gendis would never sell herself. However they create a situation that makes Gendis 'do' it with Mr Pulung involuntarily. Gendis brings a lot of money to the hospital to pay the deposit. But, her mother dies. This is the second time she gets psychological hit. The first was when she was a child. Her mother was often tortured by his father. And she saw her father committed suicide.