Fleeing from his enemies in the Catholic Church, the free thinking philosopher, poet and scientist Giordano Bruno has found some protection in Venice. But the Roman Inquisition, fearing his influence in Europe, wants to bring him on trial for 'heresy'.

Southern Italian workers relocate to Milan and adjust to life in the city, where they reside in a house together. Among the group are country boys Gigi and Carletto, who are overwhelmed by urban living. While some find work at a hectic restaurant, others are employed at a grim slaughterhouse. However, when some of the migrant workers are unable to make ends meet, they resort to theft, worsening their situations.

Sylvia, an industrial scientist, is troubled by strange hallucinations related to the tragic suicide of her mother.

A detective sick and tired of the rampant crime and violence in his city, and constantly at odds with his superiors, is finally kicked out of the department for a "questionable" shooting of a vicious criminal. However, he is soon approached by a representative for a group of citizens who themselves are fed up with what they see as criminals going unpunished, and they make him an offer he may very well not refuse.

Countess Elena marries the charming Guido Rambaldi, only for him to be seduced by dancer Nara during their Venice honeymoon.

Isabel is a dead vampire and witch whose body is hanging in a basement while the owner tries to kidnap virgins for a sacrifice that could mean Isabel’s resurrection. But doing this won’t be easy as the women aren’t gonna give in very easily.

Faccia di spia tries to tell the story of the CIA and other government intelligence agencies with lots of re-creations and dramatizations and points out some of the more brutal aspects of the intelligence community from around the world. Wars are started, all facets of everyday life are controlled, innocent people are tortured needlessly and subjected to extreme violence.

Police believe that a respectable industrialist is actually the head of drug smuggling ring in Milan.