In a world where beasts of all kinds coexist, a gentle wolf awakens to his own predatory urges as his school deals with a murder within its midst.

Vash the Stampede's a joyful gunslinging pacifist, so why does he have a $$6 million bounty on his head? That's what's puzzling rookie reporter Meryl Stryfe and her jaded veteran partner when looking into the vigilante only to find someone who hates blood.

Nina Iseri drops out of high school and moves to Tokyo by herself. In front of the station in the suburbs of Tokyo, Nina sees Momo Kawaragi singing alone and is touched by the power of music. Nina decides to form a band with Momo, Subaru Awasu, a girl who hides her true feelings, Tomo Ebutsuka, who was abandoned by her parents, and Rupa, a lonely girl without any family...