Workaholic Mike Flaherty is the Deputy Mayor of New York City, serving as Mayor Randall Winston's key strategist and much-needed handler. Mike runs the city with the help of his oddball staff: an anxious and insecure press secretary; a sexist, boorish chief of staff; an impeccably groomed gay activist running minority affairs; a sharp and efficient, man-crazy accountant; and an idealistic young speechwriter. Like Mike, they are all professionally capable but personally challenged.

Felicity Porter, a sensitive and intelligent girl from the San Francisco Bay Area, decides to give up a slot at Stanford University's pre-med program to follow her long time crush to college in New York City. Things get even more complicated when she meets her dorm's resident advisor and they fall in love.

Principal Steven Harper runs Winslow High School as best as he can while dealing with the demands of the faculty, the students and their parents.

Right out of high school, Sean Finnerty got his girlfriend Claudia pregnant. Now she’s his wife, and at just 32, he’s somehow found himself with 14-year-old daughter Lily, two little boys, and a constant struggle between his need to be responsible and his desperate desire to be irresponsible. His judgmental father Walt and devil-may-care brother Eddie are no help at all. When they all get together, stories always start to fly. Of course, Sean’s family will never let him finish a story; they interrupt, they debate, they derail, they defend themselves; just like any good family would.

Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household.

Hi Honey, I'm Home! is an American television sitcom that ran from July 19, 1991, to July 12, 1992 for 13 episodes. Each week, a new episode of the series aired on ABC as part of its Friday night TGIF lineup. The same episode would re-air Sunday night on Nickelodeon as part of the channel's Nick at Nite lineup. ABC stopped airing the series after the sixth episode of the first season. The show's second season only aired on Nick at Nite before being cancelled in July 1992. The series was taped before a live audience in Nickelodeon Studios at Universal Studios Florida.

David Hyde Pierce, playing an alien (credited as infinity-cubed in the opening credits), narrates a courtship in a late-20th century American city as an extraterrestrial nature documentary. The relationship "footage" is played straight, while the voice-over (with its most often wildly inaccurate theories) and elaborate visual metaphors add comedy.

Ping is a chihuahua rescued from the pound by nearsighted Ethel, who thinks he's a cat. When a pair of bumbling thieves try to break into Ethel's house to steal the money they think she has stashed away, only Ping can foil their plans.