A team of dedicated men and women in the Crime Investigation Department will risk everything to solve Mumbai's toughest, most complicated crimes.

In the early 70s, aspiring actor Om Prakash Makhija, and a famous starlet Shantipriya, are murdered. Thirty years later, his reincarnation Om Kapoor sets out to discover the mystery of their demise.

Reena and fellow collegian Akash Mehta are medical (psychiatry)students. They are sweethearts and hope to marry each other after completing their education. Before that could happen, Megha Joshi enters their lives and changes everything. For Akash falls head over heels in love with her, and will do anything for her. Just when their education is about to get over, Megha disappears from Akash's life.

When a delusional housewife with a personality disorder is taken hostage by a terrorist on the loose and a husband accused of cheating on his wife have their own versions of reality, how do we know who's saying the truth?

When police officer Nihaal releases a notorious criminal, Romeo, by mistake, he expects to be fired, but is instead hired by the FBI to track down and identify Romeo, who is a terrorist on the Most Wanted list. Nihaal manages to find Romeo, but rather than turning him in, he helps him escape, and winds up on the Most Wanted list himself.

Shama and Ravi are members of a Marxist party. Shama loves classical Indian music, a luxury of a few, and Ravi is in love with quotations and the philosophy of Marx - a need of the masses. Due to a strike, Ravi is compelled to work full-time for the party. Shama decides to give up music reluctantly and joins Ravi.