In a small town, a demonic form of the Easter Bunny murders everyone in its path. The residents realize that they must destroy the creature before it completes its 'Easter Holocaust' and brings about the apocalypse.

After an apocalypse nearly destroys the planet; the dead are resurrected as a result of lasting radioactivity. Without an effective means of destroying all zombies, an organization simply known as Undead Manor presents a "solution". The mastermind of the facility offers families with a means of containing their undead loved ones by housing them in "memorial cells". However, a group of guests invited to tour the facility, soon discovers that this service comes at a high price. One by one the undead begin to escape their cells, and the guests must ban together in order to survive the "Attack of the Radioactive Zombies."