Jakob Kelser is a lonely man living in a run-down house on the edge of a council estate. After enduring weeks of aggrevation and torment from local youths , Jacob, in a last-ditch attempt to once again lead a normal life, plots his revenge on his unsuspecting tormentors. One by one, they're be taught a lesson. One by one, they meet their deaths.

Docu-drama telling the story of one of the most infamous incidents in recent British medical history. On 13th March 2006, 8 healthy young men took part in a clinical trial for a leukaemia drug that went very wrong.