Wes Block is a detective who's put on the case of a serial killer whose victims are young and pretty women. The murders are getting personal when the killer chooses victims who are acquaintances of Block. Even his daughters are threatened.

A prostitute and a drifter find themselves bound together as they make their way through the rural South, doing what they have to do to survive.

In this horror-drama the festive fun of the annual Mardi Gras celebration is brought to a halt when a swarm of African killer bees escape from a foreign freighter.