Three years after the zombie virus has gutted the country, a team of everyday heroes must transport the only known survivor of the plague from New York to California, where the last functioning viral lab waits for his blood.

During the illness of her father, Toni Carter, Milly takes his place as station agent. Both Dave Snowden, a freight engineer, and Bill Mailey love her. Bill, a land express courier, who distrusts and dislikes Dave sees that both the girl and her father favor his rival and decides to disgrace the station agent and his daughter.

Tom Evans lives happily with his wife and child in their little place in Arizona until he is gripped with “Gold Fever”! He heads to Cripple Creek, strikes it rich, then abandoning his family makes his way to Chicago. Twenty years pass and he longs for his old home. Returning Tom is told by his son, now a man, there is no place for him before onlookers. Later, when Tom is found lying unconscious at the bottom of the arroyo, the son is accused and arrested. But Tom has only been stunned by his fall. He testifies that it was an accident, and reconciliation is affected between him and his long-lost family.