A high concept thriller that tells the story of Dr. Ephraim Goodweather, the head of the Center for Disease Control Canary Team in New York City. He and his team are called upon to investigate a mysterious viral outbreak with hallmarks of an ancient and evil strain of vampirism. As the strain spreads, Eph, his team, and an assembly of everyday New Yorkers, wage war for the fate of humanity itself.

Follow the mystery of Flight 716 - a passenger plane that vanishes over the Atlantic Ocean. Following the mysterious crash, recently widowed, brilliant aviation investigator Kendra Malley is called in to investigate by her former boss and mentor Howard Lawson.

As a last-ditch attempt to save his failing marriage, an actor stages a home invasion during a romantic getaway weekend.

As his mother’s illness progresses, a wealthy young man hires a perfect caregiver. But their lives start to spiral into a deadly affair as the caregiver seemingly tries to make herself a permanent facet of the wealthy family.