Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

A diverse group of recruits has arrived at the FBI Quantico Base for training. They are the best, the brightest and the most vetted, so it seems impossible that one of them is suspected of masterminding the biggest attack on New York City since 9/11.

A happily married man's life is turned upside down when his wife is killed in a mysterious hit-and-run accident in Tel Aviv. Grief-stricken and confused, he searches for his wife's killers, who have fled to the U.S. With the help of an ex-lover, he uncovers disturbing truths about his beloved wife and the secrets she kept from him.

Part horror movie, part medical detective story, find out what happens when people fall prey to an infection from a parasite, those nasty microscopic creatures found in water, soil and even in the air. Victims' stories are retold, including how doctors and scientists attempt to unravel each case before it's too late. Biologist Dan Riskin, assisted by doctors and experts who witnessed each case, leads the scientific discussion about each parasite.

In 1999, teenage sisters Celeste and Eleanor survive a seismic, violent tragedy. The sisters compose and perform a song about their experience, making something lovely and cathartic out of catastrophe — while also catapulting Celeste to stardom. By 2017, the now 31-year-old Celeste is mother to a teenage daughter of her own and struggling to navigate a career fraught with scandals when another act of terrifying violence demands her attention.

A troubled family moves to New York.