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Tells the story of Riri, a young doctor, in the course of his life, determines his best choice. we will follow Riri in taking the risks she has to live with in each of her choices. Riri realized that she couldn't keep running away and dodged. In the end he had to choose. Unfortunately every choice has a very big risk that will affect his life. Riri really hates regret. But if he had to regret, at least he wanted that regret not to sacrifice other people. Riri never loved the adventurous Haris, let alone Bandi the musician who later became close to her. He never even thought that he would be in the middle of the chaos of these two loves. In the end, it turns out that freedom is also a choice that Riri must be responsible for.

'Isyarat' takes the innovative approach of bringing together five young directors, Asmirandah, who made Teman Bayangan (Shadow friend); Monty Tiwa (Lost and Found); Adhyatmika (Flora); Donny Alamsyah (Tanda Bahaya or Alarm); and Reza Rahadian (Gadis Indigo or Indigo girl), to create a series of separate but interconnected supernatural tales.