Between the events of 'Saw' and 'Saw II', a sick and desperate John Kramer travels to Mexico for a risky and experimental medical procedure in hopes of a miracle cure for his cancer, only to discover the entire operation is a scam to defraud the most vulnerable. Armed with a newfound purpose, the infamous serial killer returns to his work, turning the tables on the con artists in his signature visceral way through devious, deranged, and ingenious traps.

Sebastián, an actor known for just one role he played years ago, is about to get engaged, but life has other plans for him. Just when his life seemed to be all mapped out, he is thrown back in the fold with his long time friends who are bad at relationships. All of the sudden, he goes back to the life he left almost 10 years ago: being single.

Michi and Marie Claire come face to face as they try to get close to the Urquiza family, one of the richest families in Mexico. There are no holds barred as to who comes out on top.

Marga and Martín meet and feel attracted to each other, not realizing they'll be neighbors.

Sofia is a single young stand up comedian trying to navigate the comedy business as well as the very traditional world in which she was brought up. She is constantly getting into trouble due to her ideas and graceless attitude. But deep down she melts at the sight of a helpless dog and would do anything for her family and friends.

Raffi, nearly forty and defiant of the system, has cycled through rehab countless times. After being kicked out of the clinic in his fifth attempt to get clean, he is forced to return to the person he despises most: his mother. Two days later, she kicks him out, and Raffi turns to Trino, his last remaining friend, for refuge. When he learns that his high school crush, Inés, is newly divorced, Raffi vows to win her over, even if it means getting a regular job, growing up, and finally taking his recovery seriously.

Sofia, an insecure young woman, begins babysitting two troublesome siblings that turn her job into a complete living hell. That is until a devilish presence starts messing with the trio and they must band together to fight the demon away.

This heartbreaking story follows young newly weds and parents Sara and Matthew Atkins, who are treated by Cecilia Pederson four weeks before she calls John Kramer. What are the tragic, life changing effects on those Cecilia Pederson scams?