Kindhearted Griffin Keyes is one of the best-loved caretakers at the Franklin Park Zoo, but he's more comfortable with the animals than with females of his own species as proven by his failed marriage proposal to the self-absorbed Stephanie several years ago. The animals have listened to Griffin pine over her for years and, after she reappears in his life, they decide to help Griffin rekindle the relationship and become the alpha male she wants him to be. They inadvertently reveal their secret ability to talk and, after Griffin's initial shock, teach him the rules of courtship, animal-style. Surprisingly, the animals' advice really works and Griffin is about to get everything he's ever dreamed of--or is he?

There are consequences when BFFs - short for best friends forever - turn into frenemies. Episodes showcase true stories of intense friendships - and, in some cases, more than that - taking a bad turn that results in the most tragic ending possible for at least one person involved in the relationship. The show serves as a reminder to viewers that not even the best of friends keep that status forever.

A set of quintuplets have had their lives documented on television. Now they are adults with professional lives

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