As America's stock of athletic young men is depleted during World War II, a professional all-female baseball league springs up in the Midwest, funded by publicity-hungry candy maker Walter Harvey. Competitive sisters Dottie Hinson and Kit Keller spar with each other, scout Ernie Capadino and grumpy has-been coach Jimmy Dugan on their way to fame.

When narcotics detective Ike Walters visits his former partner Stetson Avery in rural Greentown, he inexplicably finds himself the target in a deadly game of deceit. Befriended by the alluring yet suspicious Renee Dupa, Ike discovers that his life has been placed on the line and that nothing is what it seems.